Table 7 Logistic regression analysis for the associations between high-density cholesterol (HDL) and the risk of biological age acceleration, weighted.

From: Association of uric acid to high-density cholesterol ratio (UHR) with biological age acceleration: evidence from NHANES 2009–2018

 

Model 1

Model 2

Model 3

OR (95%CI)

p-value

OR (95%CI)

p-value

OR (95%CI)

p-value

Phenotypic age acceleration

Continuous†

0.62 (0.60,0.64)

< 0.001

0.65 (0.63,0.67)

< 0.001

0.74 (0.71,0.77)

< 0.001

Categories

      

Tertiles 1

Reference

 

Reference

 

Reference

 

Tertiles 2

0.58 (0.54,0.62)

< 0.001

0.63 (0.58,0,67)

< 0.001

0.74 (0.69,0.80)

< 0.001

Tertiles 3

0.36 (0.33,0.38)

< 0.001

0.40 (0.37,0.43)

< 0.001

0.53 (0.49,0.57)

< 0.001

p for trend

< 0.001

 

< 0.001

 

< 0.001

 

KDM age acceleration

Continuous†

0.85 (0.83,0.88)

< 0.001

0.89 (0.86,0.91)

< 0.001

0.97 (0.94,1.00)

< 0.001

Categories

      

Tertiles 1

Reference

 

Reference

 

Reference

 

Tertiles 2

0.77 (0.72,0.82)

< 0.001

0.80 (0.75,0.86)

< 0.001

0.89 (0.83,0.96)

< 0.001

Tertiles 3

0.70 (0.65,0.74)

< 0.001

0.76 (0.70,0.81)

< 0.001

0.92 (0.86,0.99)

< 0.001

p for trend

< 0.001

 

< 0.001

 

< 0.001

 
  1. Model 1 was crude model. Model 2 was adjusted for age, sex, and race. Model 3 was further adjusted for education level, alcohol consumption, smoking status, cardiovascular disease, hypertension, diabetes, cancer, and physical activity. Continuous†, standardized high-density cholesterol (HDL). p for trend was tested by incorporating the variables of the median of each quartile into the regression model.
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