Fig. 5 | Scientific Reports

Fig. 5

From: The mechanism of luteolin suppressing pancreatic cancer (PC) via cyclin B1 (CCNB1)-mediated signalling

Fig. 5

CCNB1 may be the target of luteolin on pancreatic cancer. (A) The veen diagram showed the results of network pharmacology and bioinformatics. (B) The volcano map of DEGs. (C) The heatmap of top 30 DEGs. (D) The veen diagram of network pharmacology and RNA-sequencing. (E) The expression difference of key genes between normal and tumor tissue in TCGA database. (F-I) The KM-plot of CCNB1, MMP1, NUF2 and TOP2A. The statistical significance is indicated as ***P<0.001 and **** P < 0.0001.

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