Fig. 3 | Scientific Reports

Fig. 3

From: Acute radiotoxicity studies and safety assessment of 166Ho-EDTMP and 166Ho-DOTMP for the palliative treatment of bone metastases

Fig. 3The alternative text for this image may have been generated using AI.

Microscopy images of the liver, kidney, spleen and femur tissues of the mice in all the groups (n = 5) observed on Day 14 after 0.9% NaCl, 166Ho-EDTMP and 166Ho-DOTMP injection. Tissues were stained with H&E and imaged (on an Olympus microscope, DP74, magnification 400×). White arrow: mild liver inflammation and mild internephritis area. Gray arrow: mild necrotizing hepatitis and hemorrhage. Black arrow: macrophages.

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