Fig. 3 | Scientific Reports

Fig. 3

From: Acute radiotoxicity studies and safety assessment of 166Ho-EDTMP and 166Ho-DOTMP for the palliative treatment of bone metastases

Fig. 3

Microscopy images of the liver, kidney, spleen and femur tissues of the mice in all the groups (n = 5) observed on Day 14 after 0.9% NaCl, 166Ho-EDTMP and 166Ho-DOTMP injection. Tissues were stained with H&E and imaged (on an Olympus microscope, DP74, magnification 400×). White arrow: mild liver inflammation and mild internephritis area. Gray arrow: mild necrotizing hepatitis and hemorrhage. Black arrow: macrophages.

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