Fig. 7 | Scientific Reports

Fig. 7

From: Chemical synthesis, bioinformatics and antiproliferative studies of novel pyrimidin-4-yl-1H-pyrazole derivatives in chronic myeloid cancer cells

Fig. 7

Cytotoxicity of compounds in CML imatinib sensitive (K562) and resistant (K562-IM) cell lines and normal dermal fibroblasts after 72 h incubation. Cytotoxicity of compounds 2, 2a, 2b, 2c, 3, 3a, 4 and 7 in (A) K562 cell line and (B) K562-IM cell line. Cytotoxicity of compounds 5 and 6 in (C) K562 cell line, (D) K562-IM cell line and (E) normal dermal fibroblasts. *p value < 0.05 relative to respective cells treated with DMSO.

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