Fig. 2 | Scientific Reports

Fig. 2

From: The stem ethyl acetate extract of Costus pictus D.DON exhibits cytotoxic activity in human cancer cells via. intrinsic apoptotic caspase pathway as a first report

Fig. 2

Effect of SE on cytotoxicity and cell viability on A-549 and L929 cells. (A) Neutral red uptake representative bar chart shows dose dependent elevation in cytotoxicity in A-549 cells. The level of cytotoxicity was elevated at 5–100 µg/mL concentration. (B) The in vitro MTT cytotoxicity representative bar chart shows slight cytotoxicity reactivity in L929 cells with no significant decline in the number of viable cells. Data are expressed as mean ± SD (n = 3). One-way ANOVA with Tukey’s post hoc test was performed; significance is indicated as *p < 0.05, **p < 0.01, ***p < 0.001 versus 5 µg/mL. Untreated wells (0 µg/mL) were not included; therefore, the lowest concentration tested (5 µg/mL) served as the baseline reference group for statistical comparisons.

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