Table 3 Logistic regression analysis of KRAS mutation predictors.

From: Correlation analysis between RAS gene mutations and pathological morphological features in colorectal cancer

Characteristic

Univariate analysis OR (95% Cl)

P-value

Multivariate analysis OR (95% Cl)

P-value

Right-sided colon

2.12 (1.34–3.37)

0.001*

1.85 (1.12–3.05)

0.017*

Tumor budding high

3.08 (1.85–5.13)

<0.001**

2.46 (1.38–4.39)

0.002**

Mucinous component absent

2.77 (1.51–5.06)

0.001*

2.39 (1.21–4.70)

0.012*

Moderate to severe infiltration strength

1.98 (1.19–3.31)

0.008**

1.62 (0.93–2.83)

0.088

Combined PIK3CA mutation

2.33 (1.12–4.86)

0.023*

2.15 (1.03–4.50)

0.042*

Combined TP53 mutation

0.66 (0.42–1.04)

0.074

0.59 (0.35–0.99)

0.047*

Distant metastasis​ present

1.96 (1.01–3.80)

0.056

1.64 (0.79–3.39)

0.183

  1. OR (odds ratio) > 1 indicates that the factor is positively associated with KRAS mutations; P < 0.05 is statistically significant and is marked with *.
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