Table 1 Comparison of characteristics between transplanted and nontransplanted FECD patients.

From: Risk factors for corneal transplantation in Fuchs endothelial corneal dystrophy from a large Thai cohort

 

Transplanted group

Nontransplanted group

P-value*

N

215

983

 

Age (year), mean ± SD

66.1 ± 10.0

65.2 ± 11.7

0.348

Female sex, n(%)

152 (70.7)

792 (80.6)

0.228

Diabetes mellitus, n(%)

48 (22.3)

173 (17.6)

0.465

Hypertension, n(%)

94 (43.7)

370 (37.6)

0.336

Interim intraocular surgery**, n(%)

73 (34.0)

291 (29.6)

0.001

BCVA (LogMAR), mean ± SD

0.66 ± 0.74

0.24 ± 0.40

< 0.001

Phakic lens status***, n(%)

151 (70.2)

735 (74.9)

0.613

Adamis’ grade 2 or higher, n(%)

119 (55.3)

74 (7.5)

< 0.001

Eyes with measurable ECD****, n

58

673

 

First measurable ECD (cells/mm2), mean ± SD

1406.9 ± 711.6

2182.3 ± 583.7

< 0.001

Eyes with measurable CCT****, n

158

841

 

First measurable CCT (µm), mean ± SD

618.5 ± 96.7

556.8 ± 45.9

< 0.001

  1. BCVA, best-corrected visual acuity; CCT, central corneal thickness; ECD, endothelial cell density.
  2. *Continuous data were analyzed using an independent T-test, while categorical data were analyzed using a Chi-square test.
  3. ** Interim intraocular surgery refers to procedures performed after enrollment but before keratoplasty (e.g., cataract or glaucoma surgery).
  4. *** Phakic indicates eyes with the natural crystalline lens intact; no phakic intraocular lens (phakic-IOL) cases were included.
  5. **** Variable-specific sample sizes (n) are shown for parameters with incomplete data (e.g., ECD and CCT).
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