Table 2 Brain regions showing significant differences in FC with the left middle frontal gyrus as region of interest between FAP patients and HC (Alphasim-corrected P < 0.001).

From: Enhanced interhemispheric functional connectivity in patients with functional anorectal pain

Seed

Brain region

Peak MNI coordinates

t value

Cluster size (voxels, mm3)

X

Y

Z

The left middle frontal gyrus

Right middle frontal gyrus 1

45

54

18

5.95

359 (9,693)

Right middle frontal gyrus 2

33

3

54

5.02

266 (7,182)

Left superior temporal gyrus

− 54

− 6

− 3

4.81

177 (4,779)

  1. Cluster size reported as: number of voxels (volume in mm3). Volume calculated as: number of voxels × voxel volume (27 mm3). Voxel size after normalization: 3.0 × 3.0 × 3.0 mm.
  2. FAP: functional anorectal pain; FC: functional connectivity; HC: healthy controls; MNI: Montreal Neurological Institute.