Table 3 Differences in scores of PROMIS instrument items for PCSK9i and Statins.
PROMIS 10 | Total | PCSK9i | Statins | P value |
|---|---|---|---|---|
GPH | ||||
Physical health | ||||
Baseline | 2.88 ± 0.85 | 2.93 ± 0.83 | 2.83 ± 0.87 | 0.188 |
Week 12 | 3.29 ± 0.93 | 3.39 ± 0.96 | 3.19 ± 0.89 | 0.019 |
Week 48 | 3.78 ± 1.00 | 3.90 ± 0.93 | 3.65 ± 1.05 | 0.007 |
Physical function | ||||
Baseline | 3.15 ± 0.88 | 3.17 ± 0.90 | 3.14 ± 0.86 | 0.649 |
Week 12 | 3.26 ± 1.01 | 3.30 ± 1.10 | 3.21 ± 0.91 | 0.339 |
Week 48 | 3.73 ± 0.77 | 3.79 ± 0.77 | 3.67 ± 0.76 | 0.107 |
Fatigue | ||||
Baseline | 4.08 ± 0.70 | 4.16 ± 0.66 | 4.00 ± 0.72 | 0.010 |
Week 12 | 3.97 ± 0.65 | 4.04 ± 0.70 | 3.90 ± 0.58 | 0.015 |
Week 48 | 4.29 ± 0.65 | 4.34 ± 0.64 | 4.25 ± 0.66 | 0.130 |
Pain intensity | ||||
Baseline | 4.00 ± 2.82 | 4.05 ± 2.79 | 3.95 ± 2.86 | 0.692 |
Week 12 | 1.55 ± 2.39 | 1.17 ± 1.99 | 1.94 ± 2.68 | < 0.001 |
Week 48 | 0.77 ± 1.03 | 0.80 ± 0.93 | 0.74 ± 1.13 | 0.481 |
GMH | ||||
Overall quality of life | ||||
Baseline | 2.97 ± 0.87 | 3.01 ± 0.86 | 2.94 ± 0.89 | 0.385 |
Week 12 | 3.36 ± 0.91 | 3.46 ± 0.90 | 3.26 ± 0.90 | 0.013 |
Week 48 | 3.84 ± 0.85 | 3.91 ± 0.83 | 3.77 ± 0.86 | 0.083 |
Mental health | ||||
Baseline | 3.08 ± 0.80 | 3.12 ± 0.83 | 3.04 ± 0.78 | 0.290 |
Week 12 | 3.63 ± 0.85 | 3.80 ± 0.83 | 3.45 ± 0.84 | < 0.001 |
Week 48 | 3.91 ± 0.95 | 4.01 ± 0.89 | 3.82 ± 0.99 | 0.032 |
Satisfaction with social activities | ||||
Baseline | 3.10 ± 0.86 | 3.18 ± 0.86 | 3.02 ± 0.87 | 0.049 |
Week 12 | 3.60 ± 1.05 | 3.80 ± 1.09 | 3.40 ± 0.97 | < 0.001 |
Week 48 | 4.06 ± 0.86 | 4.16 ± 0.82 | 3.95 ± 0.90 | 0.009 |
Emotional problems | ||||
Baseline | 3.84 ± 0.86 | 3.88 ± 0.87 | 3.81 ± 0.86 | 0.406 |
Week 12 | 4.15 ± 0.77 | 4.21 ± 0.77 | 4.09 ± 0.76 | 0.082 |
Week 48 | 4.16 ± 0.98 | 4.15 ± 1.02 | 4.17 ± 0.94 | 0.819 |
