Table 2 Clinicopathological characteristic of the patients (serum cohort).

From: Fibrinogen alpha and beta chains as non-invasive predictors of hepatocellular carcinoma progression

Variable

Total cohort (n = 255)

§§N (n = 30)

¶¶CH (n = 34)

†††LC (n = 33)

‡‡‡HCC (n = 158)

Age (years),

mean ± SD

34.6 ± 7.4

46.5 ± 10.5

53.1 ± 10.3

55.8 ± 9.4

Male sex, n (%)

4 (13.3)

20 (58.8)

20 (60.6)

130 (82.3)

Etiology, n (%)

 †HBV

   

145 (91.8)

v‡HCV

   

11 (7.0)

 Alcohol

   

2 (1.3)

§AST, IU/mL

16.6 ± 3.7

54.3 ± 48.3

80.7 ± 97.6

54.2 ± 61.6

¶ALT, IU/mL

13.7 ± 7.6

65.7 ± 71.8

77.0 ± 97.9

41.4 ± 37.7

Platelet, × 103/µL

294.7 ± 33.2

175.2 ± 51.2

129.4 ± 76.5

161.8 ± 73.1

††AFP (ng/mL),

mean ± SD

 

26.4 ± 31.9

65.8 ± 130.9

2632.3 ± 10815.3

Albumin (g/dL),

mean ± SD

 

4.4 ± 0.9

4.0 ± 0.5

4.3 ± 0.5

Total Bilirubin (mg/dL),

mean ± SD

 

0.8 ± 0.3

1.1 ± 1.0

0.9 ± 2.4

‡‡INR, mean ± SD

 

0.4 ± 0.6

1.0 ± 0.5

1.1 ± 0.1

Modified UICC stage, n (%)

 I

   

48 (30.4)

 II

   

79 (50)

 III

   

18 (11.4)

 IVA

   

10 (6.3)

 IVB

   

3 (1.9)

Vascular invasion,

n (%)

   

38 (24.0)

Recur, n (%)

   

72 (45.6)

  1. †HBV, hepatitis B virus; ‡HCV, hepatitis C virus; §AST, aspartate aminotransferase; ¶ALT, alanine aminotransferase; ††AFP, α-fetoprotein; ‡‡INR, international normalized ratio; §§N, Normal; ¶¶CH, chronic hepatitis; †††LC, liver cirrhosis; ‡‡‡HCC, hepatocellular carcinoma.