Fig. 3
From: Metabolomic and clinical feature analyses of plasma from influenza A patients

Metabolomic analysis of mild and severe/critical. OPLS-DA score diagram of mild and severe/critical (A and B). Volcano plot of differentially abundant metabolites between mild patients and severe/critical (C). Top 20 metabolites with the highest VIP values (D). Heatmap of the top 30 differentially abundant metabolites between mild and severe/critical (E). Enrichment analysis of the differentially abundant metabolite pathways in mild vs. severe/critical (F). *p < 0.05, **p < 0.01, ***p < 0.001, based on Mann–Whitney U test.