Table 1 Clinical characteristics of influenza patients and healthy controls.
From: Metabolomic and clinical feature analyses of plasma from influenza A patients
Characteristics | Healthy control(n = 20) | Influenza group | ||
|---|---|---|---|---|
Mild(n = 20) | Severe(n = 20) | Critical(n = 14) | ||
Basic characteristics | ||||
Gender | ||||
Male, male | 9(45.00) | 10(50.00) | 12(60.00) | 9(64.29) |
Women, women | 11(55.00) | 10(50.00) | 8(40.00) | 5(35.71) |
Thermal history, day | – | 3.00(2.00, 3.00)b | 4.00(3.00, 7.00) | 3.0, 0(2.00, 5.50) |
Highest temperature, °C | – | 39.00(38.53, 39.28) | 39.00(38.50, 39.47) | 39.00(38.05, 39.80) |
Blood routine test | ||||
WBC,×10^9/L | 6.42(5.24, 7.05) | 6.95(4.77, 7.53) | 6.16(4.95, 7.66) | 7.48(4.39, 8.85) |
HB, g/L | 144.50(132.5, 161.00) | 149.00(141.00, 157.00) | 136.50(123.75, 136.50) | 130.00(105.00, 132.00) |
PLT ×10^9/L | 277.50(190.25, 267.50)a | 224.00(218.00, 259.00)b | 180.00(144.50, 211.00) | 134.00(90.00, 260.00) |
Neu count, ×10^9/L | 3.67(2.68, 4.24)a | 4.24(2.65, 5.59) | 4.55(3.11, 5.72) | 4.62(3.77, 6.39) |
Mon count, ×10^9/L | 0.34(0.28, 0.49)a | 0.78(0.67, 0.85)b | 0.54(0.35, 0.62) | 0.22(0.20, 0.79) |
Lym count, ×10^9/L | 2.09(1.93, 2.45)a | 1.27(0.95, 1.36) | 1.22(0.81, 1.77) | 0.58(0.42, 1.17) |
C-reactive protein, mg/L | 15.30(3.82, 32.44)a | 37.20(15.40, 84.90)b | 90.04(51.72, 90.04) | 55.60(22.40, 92.80) |
Liver biochemical indicators | ||||
Total bilirubin, µmol/L | 16.55(12.38, 18.58) | 10.30(7.20, 15.90) | 8.10(6.60, 17.03) | 9.10(6.90, 15.30) |
Direct bilirubin, µmol/L | 4.74(3.60, 5.57) | 2.90(2.11, 4.38) | 3.00(2.07, 7.28) | 2.90(1.63, 5.80) |
ALT, U/L | 20.00(15.25, 29.50) | 21.70(14.00, 42.00) | 21.00(12.10, 46.50) | 31.00(14.00, 45.00) |
AST, U/L | 22.50(18.40, 32.75)a | 25.00(19.00, 49.00) | 36.30(23.60, 60.25) | 48.50(29.00, 52.00) |
Albumin, g/L | 39.40(37.50, 43.38)a | 35.50(29.70, 36.70) | 33.60(29.00, 37.48) | 33.10(29.70, 38.20) |
Globulin, g/L | 27.85(24.23, 33.33) | 28.20(25.70, 30.10) | 27.05(22.95, 29.73) | 28.90(25.50, 30.80) |
ALP, U/L | 60.00(52.25, 89.00)a | 76.00(53.00, 89.00) | 89.50(74.00, 118.25) | 87.00(56.00, 92.00) |
Myocardial enzyme spectrum indicators | ||||
LDH, U/L | 182.50(157.50, 229.50)a | 237.00(174.00, 323.00) | 311.00(207.75, 423.75) | 323.00(237.00, 411.00) |
CK, U/L | 67.50(48.00, 109.00) | 68.00(37.00, 225.00)b | 70.00(42.25, 176.75) | 83.00(28.00, 113.00) |
CK-MB, U/L | 12.00(9.83, 13.00)a | 15.00(9.10, 18.00) | 14.00(12.00, 24.70) | 15.00(9.00, 24.00) |
Indicators of renal function | ||||
Urea, µmol/L | 4.85(4.00, 5.75) | 4.80(3.40, 6.40) | 6.20(5.13, 7.70) | 5.00(3.70, 6.10) |
Creatinine, µmol/L | 58.65(45.00, 69.32) | 63.21(51.00, 72.30) | 51.50(42.50, 91.94) | 47.11(43.95, 54.80) |
Electrolyte | ||||
Sodium ion, mmol/L | 141.25(139.65, 142.85)a | 138.00(135.70, 140.10) | 139.40(137.08, 142.00) | 136.80(135.00, 138.30) |
Potassium ion, mmol/L | 3.90(3.73, 3.90) | 3.80(3.60, 4.60) | 3.97(3.81, 4.17) | 3.80(3.60, 4.40) |
Calcium ion, mmol/L | 2.17(2.10, 2.20)a | 2.09(1.99, 2.19) | 2.02(1.93, 2.17) | 2.09(1.92, 2.19) |
Phosphorus ion, mmol/L | 1.08(1.01, 1.11)a | 1.02(0.80, 1.14) | 0.85(0.71, 1.08) | 0.84(0.62, 1.01) |
