Fig. 2
The overall process of tumor habitat generation and extraction of ecological spatial features. A: Image acquisition, registration and segmentation of the region of interest. B: Cluster analysis was used to classify the voxels of the region of interest into 3 categories. C: The generation of three habitats, Habitat1, Habitat2, and Habitat3 are shown in red, green, and blue, respectively. D: Habitat images are presented in the original tumor images. E: Extraction of ecological spatial features of 3 tumor habitats and landscapes.The extracted spatial characteristics included patch area, edge and degree of aggregation, such as SHAPE, CIRCLE. F: Establishment of prediction model for metachronous metastasis of colon cancer.
