Table 2 Univariate and multivariate Cox regression analyses for landscape pattern characteristics of metachronous metastasis of the colon cancer patients.

From: Risk stratification for metachronous metastasis in colon cancer based on landscape ecological analysis

 

Univariate

 

Multivariate

 

Characteristics

HR(95%CI)

P

HR(95%CI)

P

NP

0.96 (0.91–1.01)

0.07

1.16(0.92–1.46)

0.22

LPI

1.07 (1.02–1.12)

0.01

1.17(0.93–1.47)

0.18

TE

1 (0.99–1.99)

0.06

0.99(0.99–1.00)

0.16

LSI

0.77 (0.59–1.00.59.00)

0.04

1.63(0.27–9.86)

0.6

GYRATE_MD

1.21 (0.99–1.48)

0.08

1.67(1.142–2.45)

0.008

PARA_RA

1 (0.99–1.99)

0.02

0.99(0.99–1.00)

0.55

CIRCLE_MD

0.004 (0–1.86.86)

0.08

0(0–0.41)

0.036

CIRCLE_RA

0.003 (0–4.64.64)

0.07

0.178(0–2183.99)

0.72

CONTIG_RA

0.04 (0.002–0.68)

0.02

4842.73(0.93 - Inf)

0.62

NDCA

0.96 (0.91–1.01)

0.07

NA

NA

ENN_AM

1.20 (1.04–1.39)

0.03

1.01(0.76–1.35)

0.95

DIVISION

0 (0–0.002.002)

0.01

0(0 - Inf)

0.55

MESH

7.49 (0.95–58.90)

0.10

66.17(0.03 - Inf)

0.28

AI

1.12 (0.99–1.27)

0.09

0.173(0 - Inf)

0.99

NLSI

0 (0–4.73.73)

0.09

0(0 - Inf)

0.99

  1. -HR = Hazard Ratio.NP = Number of Patches.LPI = Largest Patch Index.TE = Total Edge.LSI = Landscape Shape Index.GYRATE = Radius of Gyration Distribution.PARA = Perimeter-Area Ratio.CIRCLE = Related Circumscribing Circle.CONTIG = Contiguity Index Distribution. NDCA = Number of Disjunct Core Areas. ENN = Euclidean Nearest Neighbor Distance Distribution.DIVISION = Landscape Division Index.MESH = Effective Mesh Size.AI = Aggregation Index.NLSI = Normalised Landscape Shape Index. MD = Median.RA = Range.