Table 4 Amount of phosphine ligands dispensed into reactions. These ligands are listed based on their electronic effect (vco) and tolman’s cone angle, used to screen reactions.
From: Application of statistical design of experiment to identify key factors in cross coupling reactions
Factors | Ligands | vco(cm–1) | θ | Amount |
|---|---|---|---|---|
A & B | T1 | + 1 | + 1 | 0.0105 g/0.0523 g |
A & B | T2 | + 1 | –1 | 5.2 µL/26.21 µL |
A & B | T3 | –1 | + 1 | 0.0056 g/0.0280 g |
A & B | T4 | –1 | –1 | 2.85 µL/14.22 µL |
