Fig. 4 | Scientific Reports

Fig. 4

From: Astragalus membranaceus injection activates mitophagy and protects mitochondrial function in chronic heart failure via inhibiting AKT/mTOR pathway

Fig. 4

AMI improves myocardial mitochondrial structure and promotes mitophagy. (A) Representative Masson’s trichrome staining images. Scale bar: 50 μm. (B) Quantitative analysis of myocardial fibrosis levels (n = 3). (C) Representative TEM images. Scale bar: 1 μm, arrows indicate autophagosomes. (D) Quantitative analysis of autophagosome numbers (n = 6). (E) Immunofluorescence staining of myocardial LC3B (green), TOMM20 (red), and DAPI (blue). Scale bar: 20 μm. (F) Quantitative analysis of LC3B fluorescence intensity (n = 3). (G) Quantitative analysis of TOMM20 fluorescence intensity (n = 3). *P < 0.05 and **P < 0.01.

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