Table 3 Results of GSEA gene set enrichment analysis between IDD and control groups in combined datasets.

From: Bioinformatic analysis of glycosylation-related genes in intervertebral disc degeneration and their roles in immune infiltration and diagnostic models

ID

Set Size

Enrichment Score

NES

P value

p.adjust

Q value

KIM_WT1_TARGETS_DN

416

0.4509278

1.864365

1.02 e-10

5.39 e-07

4.72 e-07

SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP

326

0.4767721

1.921217

6.35 e-10

1.67 e-06

1.47 e-06

BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_CALU3_CELLS_UP

238

0.5088824

1.988975

1.82 e-09

3.2 e-06

2.8 e-06

NAGASHIMA_NRG1_SIGNALING_UP

163

0.5485680

2.063942

3.24 e-09

4.27 e-06

3.74 e-06

WANG_SMARCE1_TARGETS_UP

200

0.5138466

1.957534

1.32 e-08

1.4 e-05

1.22 e-05

VERHAAK_AML_WITH_NPM1_MUTATED_UP

160

0.5351318

1.965982

4.99 e-08

3.84 e-05

3.36 e-05

JAEGER_METASTASIS_DN

235

0.4819628

1.889095

5.83 e-08

3.84 e-05

3.36 e-05

RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP

378

0.4335381

1.776046

5.16 e-08

3.84 e-05

3.36 e-05

VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP

127

0.5727855

2.027521

8.32 e-08

4.88 e-05

4.27 e-05

ONDER_CDH1_TARGETS_2_UP

239

0.4829889

1.895050

1.4 e-07

7.4 e-05

6.47 e-05

FOROUTAN_INTEGRATED_TGFB_EMT_UP

118

0.5058604

1.783987

5.13 e-05

3.82 e-03

3.35 e-03

WEINMANN_ADAPTATION_TO_HYPOXIA_DN

34

0.6808293

1.928060

1.39 e-04

7.79 e-03

6.82 e-03

GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP

413

0.3475608

1.434159

5.02 e-04

1.85 e-02

1.62 e-02

WP_IRON_METABOLISM_IN_PLACENTA

10

0.8364089

1.832610

1.37 e-03

3.38 e-02

2.96 e-02

  1. KEGG, Kyoto Encyclopedia of Genes and Genomes; IDD, Intervertebral Disc Degeneration.