Table 5 Secondary non-seizure outcomes.
From: Randomised controlled trial of online behavioural sleep intervention for children with epilepsy
Secondary outcome | Timepoint (months) | N COSI | N SC | N Total | Mean (SD) at baseline COSI | Mean (SD) at baseline SC | Mean (SD) Baseline Total | Mean (SD) at timepoint COSI | Mean (SD) at timepoint SC | Mean (SD) timepoint Total | Point Estimate (SE) | 95% CI | p-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
KASC (parent) | 3 | 16 | 24 | 40 | 11.50 (2.34) | 10.54 (2.19) | 10.93 (2.27) | 13.50 (1.15) | 11.08 (1.95) | 12.05 (2.05) | 2.03 (0.48) | 1.01, 3.05 | < 0.001 |
ISI (parent) | 3 | 16 | 24 | 40 | 9.38 (5.38) | 12.88 (4.48) | 11.48 (5.10) | 8.56 (6.23) | 11.79 (6.32) | 10.50 (6.41) | 0.15 (1.45) | −2.92, 3.23 | 0.92 |
6 | 9 | 11 | 20 | 9.44 (3.28) | 13.73 (5.14) | 11.80 (4.82) | 11.00 (5.59) | 14.09 (7.30) | 12.70 (6.61) | 1.97 (1.84) | −3.14, 7.08 | 0.34 | |
Actigraphy (total sleep time minutes): Parents | 3 | 13 | 18 | 31 | 380.41 (82.77) | 405.83 (56.85) | 395.17 (68.81 | 377.01 (80.53) | 409.14 (48.10) | 395.67 (64.53) | −12.48 (15.63) | −46.25, 21.30 | 0.44 |
Actigraphy (sleep latency minutes): Parents | 3 | 13 | 17 | 30 | 24.32 (22.73) | 20.34 (16.16) | 22.07 (19.02) | 26.58 (24.80) | 18.34 (15.93) | 21.91 (20.29) | 4.94 (5.32) | −6.66,16.53 | 0.37 |
Actigraphy (sleep efficiency minutes): Parents | 3 | 13 | 17 | 30 | 78.21 (13.33) | 79.85 (12.84) | 79.14 (12.85) | 77.66 (13.89) | 82.46 (10.07) | 80.38 (11.90) | −3.15 (2.44) | −8.47,2.18 | 0.22 |
Actigraphy (total sleep time minutes): Child | 3 | 14 | 19 | 33 | 475.46 (64.37) | 471.49 (46.51) | 473.17 (53.89) | 468.61 (44.18) | 469.1(40.88) | 468.89 (41.63) | −0.05 (9.58) | −20.74, 20.64 | 1.00 |
Actigraphy (sleep latency minutes): Child | 3 | 12 | 17 | 29 | 39.71 (38.07) | 35.08 (16.51) | 37 (27.03) | 34.18 (27.84) | 40.79 (28.51) | 38.06 (27.93) | −16.35 (6.41) | −30.63, −2.07 | 0.03 |
Actigraphy (sleep efficiency minutes): Child | 3 | 12 | 17 | 29 | 74.67 (10.28) | 78.48 (7.73) | 76.90 (8.91) | 76.38 (6.83) | 77.77 (7.06) | 77.20 (6.88) | 1.10 (1.52) | −2.30, 4.50 | 0.49 |
CHEQOL | 6 | 5 | 10 | 15 | 77.4 (7.30) | 64.5 (17.44) | 68.8 (15.83) | 82.8 (17.54) | 69.3 (18.60) | 73.8 (18.81) | 2.36 (6.74) | −26.65, 31.36 | 0.76 |
Total sickness related school absence days: | 3 | 36 | 38 | 74 | 5.28 (6.9) | 6.39 (16.01) | 5.85 (12.37) | 4.14 (5.77) | 4.89 (11.65) | 4.53 (9.21) | −0.31 (1.04) | −2.40, 1.78 | 0.76 |
6 | 22 | 26 | 48 | 5.18 (6.4) | 7 (17.78) | 6.17 (13.69) | 5.05 (6.74) | 5.38 (11.02) | 5.23 (9.21) | 0.50 (2.20) | −4.03, 5.03 | 0.82 | |
Total SDQ score | 3 | 18 | 25 | 43 | 14.39 (7.48) | 18.00 (8.57) | 16.49 (8.24) | 13.78 (7.38) | 16.04 (9.19) | 15.09 (8.46) | 1.25 (0.23) | −0.89, 3.39 | 0.23 |
6 | 9 | 11 | 20 | 13.44 (5.94) | 21.91 (7.38) | 18.10 (7.89) | 13.33 (5.98) | 20.91 (6.66) | 17.50 (7.30) | −0.78 (0.95) | −3.41, 1.86 | 0.46 | |
HADS (parent) | 3 | 16 | 24 | 40 | 14.94 (8.14) | 15.75 (6.42) | 15.43 (7.07) | 14.19 (7.82) | 14.25 (8.89) | 14.23 (8.37) | 0.96 (1.26) | −1.71, 3.63 | 0.46 |
6 | 9 | 11 | 20 | 14.56 (7.63) | 17.45 (5.22) | 16.15 (6.41) | 16.67 (8.26) | 20.09 (6.93) | 18.55 (7.56) | −1.49 (2.47) | −8.36, 5.37 | 0.58 | |
WHO-5 (parent) | 6 | 9 | 11 | 20 | 72.67 (12.11) | 67.00 (18.51) | 69.55 (15.83) | 78.22 (20.47) | 71.73 (19.40) | 74.65 (19.63) | 0.87 (5.09) | −11.58, 13.32 | 0.87 |
PSAM (parent) | 3 | 16 | 24 | 40 | 5.64 (0.83) | 5.33 (0.82) | 5.46 (0.83) | 5.41 (0.81) | 5.41 (0.91) | 5.41 (0.86) | −0.31 (0.15) | −0.63, 0.02 | 0.06 |
6 | 9 | 11 | 20 | 5.64 (0.71) | 4.98 (0.84) | 5.28 (0.83) | 5.93 (0.82) | 4.98 (0.78) | 5.41 (0.92) | 0.41 (0.24) | −0.29,1.12 | 0.18 |
