Table 7 Costs, health outcomes, and results of the cost-effectiveness analysis.

From: Randomised controlled trial of online behavioural sleep intervention for children with epilepsy

Variable

SC + COSI

SC

Difference

Unadjusted within trial costs (£)*

Intervention

788 [788; 788]

0 [0; 0]

788 [788; 788]

Medication

49 [11; 101]

56 [24; 97]

−8 [−64; 54]

PLICS Admitted Patient Care

1,005 [0; 2,574]

138 [0; 464]

867 [−230; 2,470]

PLICS Emergency Care

76 [18; 148]

56 [12; 116]

20 [−65; 108]

PLICS Outpatient

558 [402; 725]

347 [233; 479]

211 [8; 417]

RUQ primary care

132 [70; 205]

159 [81; 251]

−26 [−142; 78]

Total

3,068 [1,910; 4,767]

1,184 [790; 1,708]

1,885 [581; 3,654]

Unadjusted health outcomes (CHU9D)*

Baseline utility

0.80 [0.76; 0.84]

0.82 [0.78; 0.85]

−0.01 [−0.07; 0.04]

Follow-up 1 utility

0.82 [0.79; 0.86]

0.84 [0.79; 0.88]

−0.02 [−0.07; 0.04]

Follow-up 2 utility

0.82 [0.78; 0.86]

0.83 [0.79; 0.88]

−0.02 [−0.08; 0.05]

QALYs (within trial)

0.42 [0.40; 0.43]

0.41 [0.39; 0.44]

0.00 [−0.03; 0.03]

Adjusted incremental analysis†

Costs (£)

2,021 [1,352; 3,455]

1,232 [535; 2,183]

1,232 [535; 2,183]

QALYs

0.42 [0.39; 0.45]

0.41 [0.38; 0.45]

0.0028 [−0.0326; 0.0368]

Incremental cost-effectiveness ratio (£/QALY)

-

-

433,167

  1. Note: Data are mean [95% confidence interval] for within-trial costs and health outcomes and mean [95% credibility interval] for the cost-utility analysis. *Imputed and bootstrapped data, †Based on posterior distribution of multivariate regression analyses on imputed data. PLICS: Patient Level Information Costing System data, RUQ: Resource use questionnaire.