Table 3 Alcohol and drug use and habits in BACLO-PTSD patients.

From: Effect of high-dose baclofen on post-traumatic stress disorder symptoms five years after hospitalization among critically ill patients with unhealthy alcohol use

Habits

Baclofene

N = 46

Placebo

N = 48

p-value

OR

[95%CI]

Absolute difference %

[95% CI]

Alcohol abusea, n (%)

18 (39.1%)

26 (54.2%)

0.07

0.68 [0.44 ;1.04]

−15.1 [–35.0 ; 4.9]

Active tobacco, n (%)

15 (32.6%)

17 (35.4%)

0.60

0.86 [0.49 ; 1.50]

−5.3 [−25.2 ; 14.6]

Drug use b, n (%)

0 (0%)

3 (6.3%)

0.12

/

−6.8 [−14.3 ; 0.6]

Drug detoxification attempt , n (%)

7 (15.2%)

3 (6.3%)

0.18

2.3 [0.6 ; 8.4]

8.9 [−3.5 ; 21.5]

Professional activity, n (%)

  

0.51

  

Working

13 (28.3%)

17 (35.4%)

   

Unemployed

2 (4.3%)

0 (0%)

   

Retired

21 (45.7%)

24 (50.0%)

   

Disability

10 (21.7%)

7 (14.6%)

   

Marital status, n (%)

  

0.66

  

Divorce

5/45 (11.1%)

4/44 (9.1%)

   

Single

10/45 (22.2%)

14/44 (31.8%)

   

Married

30/45 (66.7%)

26/44 (59.1%)

   

Medical follow-up by a general practitioner, n (%)

41 (89.1%)

41 (85.4%)

0.47

0.98 [0.86 ;1.10]

−2.1 [−13.2 ; 9.1]

Psychiatric follow-up, yes, n (%)

8 (17.4%)

11 (22.9%)

0.29

  

Antidepressant agents, n (%)

9 (19.6%)

7 (14.6%)

0.43

0.71 [0.32 ; 1.60]

−7.2 [−24.2 ; 9.8]

Anti-psychotic tagents, n (%)

2 (4.3%)

4 (8.3%)

0.35

1.3 [0.51 ; 3.1]

4.1 [−11.8 ; 20.0]

Cancer, n (%)

6 (13.0%)

2 (4.2%)

0.15

2.93 [0.63 ; 13.76]

8.8 [−2.9 ;20.5]

  1. aPatients were subjected to the questionnaire of the Diagnostic and Statistical Manual of Mental Disorder, 4th Edition, adapted by the NIAAA, to detect alcohol use disorder (ie, alcohol abuse or dependence).
  2. bBased on medical record or patient declaration. Here, drugs are represented by cannabis and cocaine.