Fig. 1

Detecting microRNAs in isolated adult esg-positive intestinal cells. (A). Ranked list of the microRNAs detected in each genetic condition (controls and 2 esg-specific Dcr-1 knock downs). microRNAs detected with rpkms of more than 5 in each replicate and an average of more than 10 counts across triplicated are shown. (B). Venn diagram presenting the number of microRNA’s detected (> 5 rpkm counts in each biological replicate for a specific genetic condition). 38 microRNAs were detected in all libraries. (C). Specific list of microRNAs detected in each genetic conditions (control and 2 esg-specific Dcr-1 knockdowns) which have been previously identified to play role in intestinal stem cells (mir-275 and mir-305) along with 2 microRNAs in this study (microRNAs detected with a rpkm count of more than 5 in each replicate.