Fig. 5

Tubular injury score in the renal cortex evaluated at the end of the protocol. (b) Bar graph of tubular injury score values. (a) Representative photomicrographs of renal histological changes from a C (n = 7), DAPA (n = 6), TDF (n = 7) and TDF + DAPA (n = 8) rat (x400). Values are means ± SEM. ap<0.001 vs. C; dp<0.001 vs. DAPA; hp<0.01 vs. TDF. C, control; DAPA, dapagliflozin; TDF, tenofovir.