Table 3 List of abbreviations.

From: Systems pharmacology approaches decipher the anti-cancer efficacy of ethnopharmacological agents in hepatocellular carcinoma

Abbreviation

Full term

CHM

Chinese herbal medicine

TGF-β

Transforming growth factor-beta signaling pathway

HCC

Hepatocellular carcinoma

ESCC

Esophageal squamous cell carcinoma

DLBCL

Diffuse large B-cell lymphoma

MAPK

Mitogen-activated protein kinase signaling pathway

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells signaling pathway

TNF

Tumor necrosis factor

IL-17

Interleukin-17

cAMP

Cyclic adenosine monophosphate

cGMP-PKG

Cyclic guanosine monophosphate-protein kinase G

p53

Tumor protein p53

PI3K/AKT

Phosphoinositide 3-kinase/protein kinase B

AMPK

AMP-activated protein kinase

RIG-I-like

Retinoic acid-inducible gene I-like

NOD-like

Nucleotide-binding oligomerization domain-like

PD-L1

Programmed death-ligand 1

Toll-like

Toll-like receptor

JAK-STAT

anus Kinase-Signal transducer and activator of transcription

VEGF

Vascular endothelial growth factor

Wnt

Wingless/integrated

EGFR

Epidermal Growth Factor Receptor

AP-1/BTG

Activator protein 1/B-cell translocation gene signaling pathway

DMSO

Dimethyl sulfoxide

DMEM

Dulbecco’s modified eagle medium

FBS

Fetal bovine serum

MTT

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay

BRPS

Bicinchoninic acid reducing protein assay

Annexin-VFITC/PI

Annexin V-fluorescein Isothiocyanate/propidium iodide staining

DEG

Differentially expressed genes

DEP

Differentially expressed protein

GO

Gene ontology

KEGG

Kyoto encyclopedia of genes and genomes

WGCNA

Weighted gene coexpression network analysis

SDC

Sodium deoxycholate

BCA

Bicinchoninic acid

TCEP

Tris (2-carboxyethyl) phosphine

CAA

Chloroacetamide

DIA

Data-independent acquisition

LSDs

Least significant differences

TME

Tumor microenvironment

PKAs

Protein kinases

CAFs

EPACs

Cancer-associated fibroblasts

Exchange proteins activated

NAFLD

Nonalcoholic fatty liver disease

EMT

Epithelial-mesenchymal transition

PCA

Principal component analysis