Table 1 Trends in stroke and DM-related mortality counts and AAMR in the united States, 1999–2023.

From: Temporal trends and disparities in stroke and diabetes mellitus comorbidity-related mortality from 1999 to 2023

Characteristic

Deaths

AAMR

1999

2023

percent.change(%)

1999(95%)

2023(95%)

AAPC (95% CI)

Stroke

137,516

103,570

− 24.69

78.24 (77.82 to 78.65)

38.20 (37.96 to 38.43)

− 2.88 (− 3.52 to − 2.23)*

DM

68,199

94,875

39.11

38.56 (38.27 to 38.85)

34.48 (34.25 to 34.70)

− 0.48 (− 0.97 to 0.02)

Both

29,045

26,940

− 7.25

16.47 (16.28 to 16.66)

9.70 (9.58 to 9.81)

− 2.32 (− 3.22 to − 1.42)*

Sex

Female

16,751

12,704

− 24.16

15.61 (15.37 to 15.84)

8.16 (8.02 to 8.30)

− 2.67 (− 3.45 to − 1.90)*

Male

12,294

14,236

15.80

17.66 (17.34 to 17.97)

11.50 (11.31 to 11.70)

− 1.90 (− 2.78 to − 1.02)*

Census Region

Northeast

5115

3576

− 30.09

13.61 (13.24 to 13.99)

6.93 (6.70 to 7.16)

− 2.50 (− 3.51 to − 1.48)*

Midwest

7280

5027

− 30.95

17.20 (16.80 to 17.59)

8.66 (8.42 to 8.90)

− 2.84 (− 3.94 to − 1.73)*

South

10,512

12,293

16.94

16.96 (16.63 to 17.28)

11.59 (11.39 to 11.80)

− 1.65 (− 2.74 to − 0.54)*

West

6138

6044

− 1.53

17.64 (17.20 to 18.08)

9.67 (9.42 to 9.91)

− 2.55 (− 3.88 to − 1.21)*

Race

 

Hispanic

1754

3164

80.39

20.94 (19.92 to 21.95)

11.23 (10.83 to 11.63)

− 2.84 (− 4.13 to − 1.52)*

NH Black

4874

4910

0.74

33.42 (32.47 to 34.36)

18.04 (17.52 to 18.56)

− 2.80 (− 4.29 to − 1.28)*

NH White

21,454

17,073

− 20.42

14.33 (14.14 to 14.52)

8.35 (8.22 to 8.48)

− 2.20 (− 2.82 to − 1.58)*

NH Other

883

1717

94.45

19.81 (18.44 to 21.17)

9.03 (8.59 to 9.46)

− 3.28 (− 4.67 to − 1.87)*

Urbanization#

Metropolitan

22,791

21,360

− 6.28

15.93 (15.73 to 16.14)

10.32 (10.18 to 10.45)

− 2.39 (− 3.04 to − 1.73)*

Nonmetropolitan

6254

5580

− 10.78

18.59 (18.12 to 19.05)

13.82 (13.47 to 14.18)

− 1.47 (− 2.17 to − 0.78)*

Age##

25–34 years

47

48

2.13

0.12 (0.09 to 0.16)

0.11 (0.08 to 0.14)

− 0.27 (− 1.09 to 0.57)

35–44 years

258

300

16.28

0.57 (0.50 to 0.64)

0.68 (0.60 to 0.75)

0.55 (− 2.26 to 3.44)

45–54 years

978

1108

13.29

2.67 (2.51 to 2.84)

2.74 (2.58 to 2.90)

− 0.02 (− 1.75 to 1.74)

55–64 years

2581

3413

32.24

10.85 (10.44 to 11.27)

8.15 (7.88 to 8.43)

− 1.40 (− 2.54 to − 0.25)*

65–74 years

6818

6827

0.13

37.02 (36.14 to 37.89)

19.68 (19.22 to 20.15)

− 2.62 (− 3.65 to − 1.58)*

75–84 years

11,379

8863

− 22.11

93.08 (91.37 to 94.79)

48.25 (47.25 to 49.26)

− 2.82 (− 3.76 to − 1.87)*

85 + years

6984

6381

− 8.63

168.13 (164.18 to 172.07)

103.00 (100.48 to 105.53)

− 2.11 (− 3.10 to − 1.11)*

  1. Statistical significance of AAPC estimates was denoted by *. #For urbanization-level classifications in the 2023 AAMR data, the 2020 classification standards were applied. AAPC calculations encompassed the period from 1999 to 2023. ##Age-stratified AAMR values were based on crude mortality rates, with corresponding AAPCs derived from these crude rates. DM: Diabetes Mellitus. AAMR: Age-adjusted mortality rate. CI: Confidence Interval.AAPC: Average annual percent changes.
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