Fig. 2
BGLSP induces apoptosis in PTC cell lines. (A, D, G) Flow cytometric quantification of apoptotic populations in TPC-1, K1 and KTC-1 cells treated with BGLSP (0.5–4.5 mg/mL, 24 h; n = 3). (B, C, E, F, H, I) Western blot analysis of caspase cascade activation (caspase-8 and cleaved caspase-3) following 1 mg/mL BGLSP treatment (n = 3). Data shown as mean ± SD. Statistical significance was determined by unpaired Student’s t-test. *P < 0.05, **P < 0.01, ***P < 0.001. Original blots are presented in Supplementary Fig. 5A.
