Table 3 Baseline characteristics of participants without MetS according to Sex-Specific tertiles of serum Irisin and adiponectin Levels.

From: Longitudinal associations of serum Irisin and adiponectin with incident metabolic syndrome in middle-aged and older adults over three years

 

Irisin (n = 188)

Adiponectin (n = 188)

Variable

Tertile 1 (n = 64)

Tertile 2 (n = 62)

Tertile 3 (n = 62)

p-valuea

Tertile 1 (n = 64)

Tertile 2 (n = 62)

Tertile 3 (n = 62)

p-valuea

Age (years)

70.0

[65.5–73.0]

71.0

[66.0–73.0]

71.5

[64.0–74.0]

0.9

71.0

[64.0–73.0]

70.0

[64.0–74.0]

70.5

[66.0–74.0]

0.488

Sex, n (%)

   

1

   

1

Male

31 (48.4%)

30 (48.4%)

30 (48.4%)

 

31 (48.4%)

30 (48.4%)

30 (48.4%)

 

Female

33 (51.6%)

32 (51.6%)

32 (51.6%)

 

33 (51.6%)

32 (51.6%)

32 (51.6%)

 

Alcohol, n (%)

   

0.003

   

0.544

Non-drinker

52 (81.2)

47 (75.8)

34 (54.8%)

 

43 (67.2%)

43 (69.4%)

47 (75.8%)

 

Drinker

12 (18.8)

15 (24.2)

28 (45.2%)

 

21 (32.8%)

19 (30.6%)

15 (24.2%)

 

Smoking, n (%)

  

0.119

   

0.848

Non-smoker

60 (93.8%)

52 (83.9%)

51 (82.3%)

 

55 (85.9%)

53 (85.5%)

55 (88.7%)

 

Smoker

4 (6.2%)

10 (16.1%)

11 (17.7%)

 

9 (14.1%)

9 (14.5%)

7 (11.3%)

 

Regular exercise, n (%)

  

0.469

   

0.525

No

42 (65.6%)

46 (74.2%)

46 (74.2%)

 

48 (75.0%)

45 (72.6%)

41 (66.1%)

 

Yes

22 (34.4%)

16 (25.8%)

16 (25.8%)

 

16 (25.0%)

17 (27.4%)

21 (33.9%)

 

Comorbidity, n (%)

  

0.159

   

0.499

0

25 (39.1%)

35 (56.4%)

36 (58.0%)

 

32 (50.0%)

30 (48.4%)

34 (54.8%)

 

1

26 (40.6%)

20 (32.3%)

20 (32.3%)

 

23 (35.9%)

20 (32.3%)

23 (37.1%)

 

≥ 2

13 (20.3%)

7 (11.3%)

6 (9.7%)

 

9 (14.1%)

12 (19.3%)

5 (8.1%)

 

BMI (kg/m²)

23.0 ± 2.7

23.4 ± 2.6

23.8 ± 2.7

0.217

24.3 ± 2.8

23.4 ± 2.6

22.5 ± 2.4

0.001

WC (cm)

80.3 ± 7.7

81.5 ± 6.0

83.2 ± 7.5

0.065

84.3 ± 6.6

81.4 ± 7.1

79.3 ± 7.0

< 0.001

SBP (mmHg)

137.0

[126.5–146.0]

139.0

[129.0–152.0.0.0]

136.0

[128.0–149.0.0.0]

0.766

138.5

[129.5–155.0]

133.5

[124.0–149.0.0.0]

137.0

[128.0–145.0.0.0]

0.178

DBP (mmHg)

80.5

[75.5–90.0]

81.0

[73.0–89.0]

83.0

[79.0–90.0]

0.734

82.5

[79.0–90.0]

82.5

[75.0–90.0]

80.0

[73.0–88.0]

0.396

FG (mg/dL)

95.0

[89.0–103.0.0.0]

94.0

[91.0–98.0]

93.0

[89.0–97.0]

0.323

95.0

[90.0–99.0]

93.5

[89.0–98.0]

93.0

[89.0–99.0]

0.62

TG (mg/dL)

95.5

[66.5–107.0]

107.0

[76.0–132.0.0.0]

112.0

[75.0–149.0.0.0]

0.01

112.0

[90.5–153.5.5.5]

105.5

[73.0–135.0.0.0]

82.0

[52.0–110.0.0.0]

< 0.001

HDL-C (mg/dL)

54.0

[45.5–62.0]

54.0

[46.0–61.0]

52.0

[46.0–60.0]

0.515

53.0

[47.0–57.5.0.5]

54.5

[44.0–64.0]

53.5

[46.0–62.0]

0.695

LDL-C (mg/dL)

110.0

[88.0–123.5.0.5]

112.5

[94.0–129.0.0.0]

116.5

[90.0–128.0.0.0]

0.557

116.0

[94.0–137.5.0.5]

112.5

[87.0–127.0.0.0]

110.0

[88.0–122.0.0.0]

0.168

HOMA-IR

1.55

[0.96–2.23]

1.61

[1.15–2.55]

1.58

[1.04–2.22]

0.775

1.63

[1.20–2.60]

1.56

[1.02–2.40]

1.46

[0.95–2.19]

0.386

hs-CRP (mg/L)

0.07

[0.04–0.13]

0.08

[0.05–0.17]

0.10

[0.06–0.20]

0.08

0.11

[0.06–0.21]

0.08

[0.04–0.17]

0.07

[0.04–0.11]

0.001

Irisin (ng/mL)

18.4

[12.1–24.1]

40.3

[34.1–51.3]

78.0

[65.0–110.2.0.2]

< 0.001

52.7

[35.4–76.3]

35.3

[21.7–65.0]

34.9

[15.4–55.3]

0.001

Adiponectin (µg/mL)

12.6 [9.6–17.7]

12.2 [6.5–16.6]

8.9 [6.8–13.7]

0.008

6.3 [4.9–8.2]

11.4 [9.3–13.7]

18.9 [16.4–21.7]

< 0.001

  1. BMI, Body mass index; WC, Waist circumference, SBP, systolic blood pressure; DBP, diastolic blood pressure; FG, fasting glucose; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hs-CRP, high-sensitivity C-reactive protein.
  2. Data are presented as mean ± SD for normal distributions, median (25th-75th quartile) for non-normal distributions.
  3. aStatistical analyses used ANOVA for normal distributions, Kruskal-Wallis for non-normal distributions, and chi-squared tests for categorical variables.
Back to article page