Table 2 Results of subgroup analysis based on different implementing entities.

From: Systematic review of healthcare-led and lay-led interventions for type 2 diabetes in community settings

Outcome

Number of RCTs

Heterogeneity

Meta analysis

Subgroup differences

P value

\({I}^{2}\)(%)

Effect estimate (95%CI)

P value

HbA1c(%)

2824,25,26,27,28,29,30,31,32,33,35,36,37,38,39,40,41,42,44,45,46,47,48,49,50,51,52,53

 < 0.00001

91

− 0.56(− 0.68,− 0.44)

 < 0.00001

0.0002

Healthcare professionals

1724,25,26,27,28,29,30,31,33,35,36,37,38,40,42,44,52

 < 0.00001

93

− 0.69(− 0.85,− 0.54)

 < 0.00001

 

Non-healthcare professionals

1132,39,41,45,46,47,48,49,50,51,53

0.03

51

− 0.30(− 0.44,− 0.17)

 < 0.0001

 

2h-PPG(mmol/L)

1124,25,26,27,29,31,33,35,36,37,53

 < 0.00001

81

− 1.82(− 2.32,− 1.33)

 < 0.00001

0.0007

Healthcare professionals

1024,25,26,27,29,31,33,35,36,37

 < 0.0001

77

− 1.96(− 2.43,− 1.49)

 < 0.00001

 

Non-healthcare professionals

153

  

− 0.45(− 1.43,0.53)

0.37

 

FPG(mmol/L)

1924,25,26,27,28,29,30,31,32,33,35,36,37,38,39,42,44,46,52

 < 0.00001

83

− 0.99(− 1.18,− 079)

 < 0.00001

0.98

Healthcare professionals

1624,25,26,27,28,29,30,31,33,35,36,37,38,42,44,52

 < 0.00001

85

− 0.97(− 1.18,− 0.77)

 < 0.00001

 

Non-healthcare professionals

432,39,46,53

0.02

68

− 0.98(− 1.70,− 0.26)

0.007

 

TC(mmol/L)

1324,25,26,28,32,33,36,37,39,40,44,46,49

 < 0.00001

93

− 0.31(− 0.55,− 0.08)

 < 0.00001

0.34

Healthcare professionals

924,25,26,28,33,36,37,40,44

 < 0.00001

95

− 0.45(− 0.71,0.01)

0.06

 

Non-healthcare professionals

432,39,46,49

0.02

71

− 0.14(− 0.38,0.11)

0.27

 

HDL(mmol/L)

1124,25,26,28,33,36,37,39,40,44,46

 < 0.00001

93

0.07(− 0.01,0.14)

0.10

0.47

Healthcare professionals

924,25,26,28,33,36,37,40,44

 < 0.00001

94

0.08(− 0.03,0.18)

0.14

 

Non-healthcare professionals

239,46

0.11

60

0.03(− 0.07,0.12)

0.60

 

LDL(mmol/L)

1424,25,26,28,33,36,37,39,40,42,44,46,50,52

 < 0.00001

100

− 0.35(− 1.01,0.32)

0.30

0.62

Healthcare professionals

1124,25,26,28,33,36,37,40,42,44,52

 < 0.00001

100

− 0.39(− 1.16,0.37)

0.31

 

Non-healthcare professionals

339,46,50

0.80

0

− 0.20(− 0.33,− 0.06)

0.005

 

TG(mmol/L)

1424,25,26,28,29,33,36,37,38,39,40,44,46,53

 < 0.00001

98

− 0.65(− 0.94,− 0.36)

 < 0.00001

0.06

Healthcare professionals

1124,25,26,28,29,33,36,37,38,40,44

 < 0.00001

97

− 0.38(− 0.65,− 0.11)

0.006

 

Non-healthcare professionals

339,46,53

 < 0.00001

99

− 2.30(− 4.30,− 0.31)

0.002

 

BMI(Kg/m2)

1124,25,26,33,37,39,41,44,50,51,53

 < 0.00001

78

− 1.34(− 1.88,− 0.81)

 < 0.00001

0.18

Healthcare professionals

624,25,26,33,37,44

0.003

72

− 1.63(− 2.32,− 0.95)

 < 0.00001

 

Non-healthcare professionals

539,41,50,51,53

0.01

70

− 0.97(− 1.65,− 0.29)

0.005

 
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