Fig. 2 | Scientific Reports

Fig. 2

From: LINC01116 promotes nascent protein synthesis and cellular stemness through the miR-432-5p/FKBP7/14 regulatory axis in melanoma

Fig. 2

LINC01116-associated mRNA co-expression and regulatory networks. (A) Venn diagram illustrating the intersection of predicted LINC01116-targeting miRNAs (identified via the Starbase database, http://starbase.sysu.edu.cn) and co-expressed mRNAs. (B) ceRNA (competing endogenous RNA) network constructed using Cytoscape 3.9.0, comprising LINC01116, four miRNAs, and 87 mRNAs. (C) Heatmap analysis of overlapping targets derived from the GEO dataset GSE15605 and TCGA database, revealing 13 shared genes in the Venn diagram. (D) Correlation heatmap of overlapping targets, demonstrating a strong positive correlation between FKBP7 /14 expression (r > 0.8, p < 0.001).

Back to article page