Fig. 8
From: Genomic analysis unlocks the potential of denosumab as a targeted therapy for Crohn’s disease
This analysis shows that the target gene TNFSF11 is localized in gastrointestinal tracts, which differs to the other 4 genes (TGFBR2, NOD2, IL6R, SH2B3) that have variation in expression in each organ, proposing a more organ-targeted therapy in CD. This figure obtained from https://gtexportal.org.
