Table 2 Comparison of the short- and long-term major clinical outcomes in patients with GIB admitted on PPIs versus off PPIs.

From: Proton pump inhibitors have no effect on short or long term rebleeding or mortality in patients with overt gastrointestinal bleeding

  

No PPIs upon admission

(n = 461)

PPIs upon admission

(n = 385)

P-value

Mortality

In-hospital

29 (6.3%)

44 (11.4%)

0.008

1-month

38 (8.2%)

60 (15.6%)

< 0.001

1-year

84 (18.2%)

119 (30.9%)

< 0.001

End of follow-up

187 (40.6%)

218 (56.6%)

< 0.001

Rebleeding

In-hospital

21 (4.6%)

26 (6.8%)

0.165

1-month

44 (9.5%)

36 (9.4%)

0.924

1-year

73 (15.8%)

57 (14.8%)

0.679

End of follow-up

96 (20.8%)

75 (19.5%)

0.628