Fig. 1

Two-dimensional (2D) topology of ABCB4 illustrating the position of the four variants studied here. A: Walker A motif, B: Walker B motif, C: signature motif for ABC transporters, MSD: membrane-spanning domain, NBD: nucleotide-binding domain.

Two-dimensional (2D) topology of ABCB4 illustrating the position of the four variants studied here. A: Walker A motif, B: Walker B motif, C: signature motif for ABC transporters, MSD: membrane-spanning domain, NBD: nucleotide-binding domain.