Figure 3 | Scientific Reports

Figure 3

From: Leveraging magnetic resonance imaging to assess biocompatible scaffolds diffusion and flow-driven perfusion for lab-on-a-chip systems

Figure 3

Diffusion studies of commonly used biocompatible scaffolds using MRI. Sagittal proton images at different times of an Eppendorf containing D\(_2\)O and a water-saturated 10% PEGDA hydrogel (A) or 1% CMC cryogel (D). The pixel threshold was individually adjusted in each image to improve visualization. For each image shown, a kernel density estimation of the pixel intensity inside the container for both the hydrogel (B) and the cryogel (E) is displayed, indicating a starting point of a distribution with a long right tail (high proton signal located in a small spatial region) evolving to a normal distribution due to the diffusion of water particles in the whole Eppendorf. Plots of the mean pixel intensity for the scaffold region (green) and the rest of the container (blue) for all images acquired every 3 minutes and 48 seconds during 4 h and 22 min for the PEGDA hydrogel (C) and 1 hour and 54 min for the CMC cryogel (F). In both plots, the vertical lines specify the time frames of the MRI images.

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