Table 2 Distribution of LiverToxA Drugs on 8,215 patients with atrial fibrillation.
Characteristic | No LiverTox A Drugs, N = 4,799 | At least One LiverTox A, N = 3,416 | N, Overall = 8,215 | p-value |
|---|---|---|---|---|
Total N Drugs | < 0.001 | |||
1–4 | 3,047 (63%) | 617 (18%) | 3,664 (45%) | |
5–9 | 1,705 (36%) | 2,512 (74%) | 4,217 (51%) | |
≥ 10 | 47 (1.0%) | 287 (8.4%) | 334 (4.1%) | |
LiverTox A Drugs | < 0.001 | |||
0 | 4,799 (100%) | 0 (0%) | 4,799 (58%) | |
1 | 0 (0%) | 2,670 (78%) | 2,670 (33%) | |
≥ 2 | 0 (0%) | 746 (22%) | 746 (9.1%) | |
LiverTox A [HD] Drugs | < 0.001 | |||
0 | 3,874 (81%) | 2,174 (64%) | 6,048 (74%) | |
1 | 886 (18%) | 1,143 (33%) | 2,029 (25%) | |
≥ 2 | 39 (0.8%) | 99 (2.9%) | 138 (1.7%) | |
LiverTox B Drugs | < 0.001 | |||
0 | 3,011 (63%) | 1,673 (49%) | 4,684 (57%) | |
1 | 1,377 (29%) | 1,274 (37%) | 2,651 (32%) | |
≥ 2 | 411 (8.6%) | 469 (14%) | 880 (11%) | |
LiverTox B [HD] Drugs | 0.173 | |||
0 | 4,799 (100%) | 3,414 (100%) | 8,213 (100%) | |
1 | 0 (0%) | 2 (< 0.1%) | 2 (< 0.1%) | |
LiverTox C Drugs | < 0.001 | |||
0 | 972 (20%) | 345 (10%) | 1,317 (16%) | |
1 | 1,924 (40%) | 1,059 (31%) | 2,983 (36%) | |
≥ 2 | 1,903 (40%) | 2,012 (59%) | 3,915 (48%) | |
LiverTox D Drugs | < 0.001 | |||
0 | 2,486 (52%) | 1,462 (43%) | 3,948 (48%) | |
1 | 1,788 (37%) | 1,348 (39%) | 3,136 (38%) | |
≥ 2 | 525 (11%) | 606 (18%) | 1,131 (14%) | |
LiverTox E Drugs | < 0.001 | |||
0 | 2,388 (50%) | 1,064 (31%) | 3,452 (42%) | |
1 | 1,406 (29%) | 1,250 (37%) | 2,656 (32%) | |
≥ 2 | 1,005 (21%) | 1,102 (32%) | 2,107 (26%) | |
LiverTox E* Drugs | < 0.001 | |||
0 | 4,158 (87%) | 2,838 (83%) | 6,996 (85%) | |
1 | 588 (12%) | 530 (16%) | 1,118 (14%) | |
≥ 2 | 53 (1.1%) | 48 (1.4%) | 101 (1.2%) | |
LiverTox X Drugs | 0.179 | |||
0 | 4,775 (99%) | 3,391 (99%) | 8,166 (99%) | |
1 | 24 (0.5%) | 25 (0.7%) | 49 (0.6%) | |
LiverTox NS Drugs | < 0.001 | |||
0 | 4,041 (84%) | 2,589 (76%) | 6,630 (81%) | |
1 | 667 (14%) | 732 (21%) | 1,399 (17%) | |
≥ 2 | 91 (1.9%) | 95 (2.8%) | 186 (2.3%) |
