Table 4 Area under the ROC curve analysis of insulin resistance surrogate indices for hypertension prediction by sex.

From: Association of surrogate indices of insulin resistance with hypertension: a cross-sectional analysis from PERSIAN Dena cohort study (PDCS)

 

AUC*

SE (%95 CI)

P-value

Sensitivity (%)

Specificity (%)

Cutoff point

Youden index

TyG Index

Overall

0.623

0.02 (0.58–0.67)

< 0.001

62

60

8.88

0.22

Male

0.642

0.03 (0.59–0.69)

< 0.001

68

58

8.87

0.26

Female

0.569

0.4 (0.5–0.64)

0.07

65

50

8.72

0.15

VAI

Overall

0.568

0.02 (0.52–0.61)

< 0.001

77

36

1.53

0.13

Male

0.614

0.03 (0.56–0.67)

< 0.001

66

46

1.76

0.12

Female

0.53

0.04 (0.46–0.61)

0.43

53

56

2.36

0.09

LAP

Overall

0.624

0.02 (0.58–0.66)

< 0.001

87

35

35.72

0.22

Male

0.667

0.025(0.62–0.72)

< 0.001

85

55

35.7

0.3

Female

0.586

0.04 (0.52–0.66)

0.024

92

23

33.98

0.15

MET-IR

Overall

0.652

0.02 (0.61–0.69)

< 0.001

94

30

35.7

0.24

Male

0.707

0.024(0.66–0.75)

< 0.001

94

63

35.7

0.31

Female

0.606

0.3 (0.54–0.67)

0.007

67

51

41.88

0.18

TYG-WC

Overall

0.647

0.02 (0.61–0.69)

0.003

90

34

783.4

0.24

Male

0.695

0.024 (0.65–0.74)

< 0.001

80

53

826.2

0.33

Female

0.599

0.034(0.53–0.67)

0.01

92

27

776.5

0.19

TYG-BMI

Overall

0.660

0.02 (0.62–0.7)

< 0.001

79

47

227.4

0.26

Male

0.712

0.024(0.66–0.76)

< 0.001

76

58

227.5

0.34

Female

0.623

0.033(0.56–0.69)

0.001

97

24

210.35

0.21

TG/HDL

Overall

0.591

0.02 (0.55–0.64)

< 0.001

65

52

2.67

0.18

Male

0.612

0.03 (0.56–0.67)

< 0.001

71

52

2.7

0.19

Female

0.534

0.04 (0.46–0.61)

0.39

55

58

2.67

0.13

AIP

Overall

0.591

0.023 (0.55–0.64)

< 0.001

65

52

0.07

0.18

Male

0.612

0.03 (0.56–0.67)

< 0.001

71

48

0.07

0.19

Female

0.534

0.04 (0.46–0.61)

0.038

55

58

0.07

0.13

  1. AUC, SE Standard error AIP, atherogenic index of plasma, LAP lipid accumulation product, METS-IR metabolic score for insulin resistance, OR odds ratio, TyGindex triglyceride glucose, TyG-BMI TyG index with body mass index, TyG-WC TyG index with waist circumference, TG/HDL-C the ratio of triglycerides to high-density lipoprotein cholesterol ratio, VAI visceral obesity index. * AUC for Receiver operating characteristic (ROC) curve analysis.