Table 3 Changes in exploratory outcomes (n = 18).

From: Feasibility of a 4-week combined supervised and home-based exercise program for patients with nontuberculous mycobacterial pulmonary disease: a single-center, single-arm feasibility study

Variable

Baseline

4 weeks

P value

Cardiorespiratory fitness

VO₂max (mL/kg/min)

29.8 (26.2 − 33.4)

28.6 (24.1 − 33.2)

0.777

Functional capacity

6MWD (m)

594.0 (553.4 − 634.6)

614.0 (554.9 − 673.1)

0.008

30-s STS (reps)

13.0 (10.5 − 15.5)

16.5 (14.3 − 18.8)

0.010

Handgrip strength (kg)

23.6 (18.7 − 28.6)

23.7 (18.8 − 28.7)

< 0.001

SPPB (score)

12.0 (12.0 − 12.0)

12.0 (12.0 − 12.0)

0.157

Pulmonary function

FVC (L)

2.80 (2.3 − 3.3)

2.77 (2.2 − 3.2)

0.827

FVC (% predicted)

87.0 (79.0 − 95.0)

86.5 (77.5 − 95.5)

0.600

FEV₁ (L)

1.84 (1.3 − 2.3)

1.96 (1.5 − 2.5)

0.813

FEV₁ (% predicted)

78.0 (70.5 − 85.5)

83.0 (73.5 − 92.5)

0.126

FEV₁/FVC (%)

75.0 (68.5 − 81.5)

74.0 (68.0 − 80.0)

0.173

Body composition

Fat mass (kg)

10.9 (7.9 − 13.9)

11.0 (7.5 − 14.5)

0.522

Skeletal muscle mass (kg)

19.5 (17.9 − 21.1)

19.4 (18.1 − 20.7)

0.275

QOL_B domain

Physical functioning

76.7 (51.6–81.7)

83.3 (60.0–93.3)

0.184

Role functioning

90.0 (66.6–95.0)

83.3 (73.3–100.0)

0.467

Vitality

66.6 (33.3–66.6)

61.1 (52.7–77.7)

0.040

Emotional functioning

75.0 (66.6–93.7)

87.5 (72.9–100.0)

0.120

Social functioning

83.3 (72.9–91.6)

79.2 (66.6–91.6)

1.000

Health perceptions

45.8 (31.2–52.1)

41.6 (31.2–58.3)

0.304

Respiratory symptoms

87.0 (75.9–93.4)

85.1 (71.2–93.4)

0.897

  1. Data are presented as median (interquartile range). Abbreviations: VO₂max, maximal oxygen uptake; 6MWD, 6-minute walk distance; 30-s STS, 30-second sit-to-stand test; SPPB, Short Physical Performance Battery; FEV₁, forced expiratory volume in 1 s; FVC, forced vital capacity; QOL-B, Quality of Life-Bronchiectasis.
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