Table 2 Association of 2-h plasma glucose during OGTT (categorical, < 140 versus ≥ 140 mg/dL) with pre-diabetes diagnosis.

From: Postprandial 2-h glucose tolerance is associated with diabetes diagnosis, diabetes mortality, and cardiovascular mortality

Models

2-h PGOGTT@4–7.9 h

2-h PGOGTT@fasting

OR

95% CI

p

OR

95% CI

p

Model 1

1.42

1.18–1.71

< 0.001

2.22

1.91–2.58

< 0.001

Model 2

1.39

1.13–1.70

0.002

2.03

1.73–2.38

< 0.001

Model 3

1.29

1.04–1.59

0.018

1.90

1.61–2.24

< 0.001

Model 4

1.36

1.10–1.69

0.004

2.00

1.69–2.36

< 0.001

Model 5

1.30

1.04–1.61

0.019

2.01

1.70–2.39

< 0.001

Model 6

1.29

1.04–1.60

0.021

2.00

1.68–2.37

< 0.001

  1. Pre-diabetes diagnosis was defined as HbA1c ranging between 5.7% and 6.4%. Out of 2347 participants in the postprandial cohort, 230 had an HbA1c value of ≥ 6.5% and were excluded from the analysis. So, a total of 2117 participants were included in the final analysis. 2-h PGOGTT@4–7.9 h, 2-hour plasma glucose during OGTT which was conducted in the postprandial period between 4 and 7.9 h; 2-h PGOGTT@fasting, 2-hour plasma glucose during OGTT which was conducted in the fasting period (fasting time, ≥ 8 h); CI, confidence interval; HbA1c, hemoglobin A1c; OGTT, oral glucose tolerance test; OR, odds ratio.
  2. Model 1 was not adjusted; Model 2 was adjusted for age, sex, and ethnicity; Model 3 was adjusted for all the factors in Model 2 plus body mass index, poverty–income ratio, and education; Model 4 was adjusted for all the factors in Model 3 plus physical activity, alcohol consumption, smoking status, and survey period; Model 5 was adjusted for all the factors in Model 4 plus total cholesterol, HDL cholesterol, and systolic blood pressure; and Model 6 was adjusted for all the factors in Model 5 plus family history of diabetes.
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