Table 1 List of proteins with a greater abundance in the IgA-ICs of patients with IgAN compared with healthy controls.

From: Complement proteins associated with circulatory and glomerular IgA-containing immune complexes in patients with IgA nephropathy

Protein name

Gene symbol

P value

Fold change

PSMs

Unique peptides

Lactotransferrin

LTF

0.0001*

7.06

58

10

Complement factor H-related protein 1

CFHR1

< 0.0001*

5.79

801

3

Keratin-associated protein 13 − 4

KRTAP13-4

< 0.0001*

4.03

4

2

Immunoglobulin heavy variable 5-10-1

IGHV5-10-1

0.0001*

3.91

615

1

Immunoglobulin lambda constant 7

IGLC7

0.0002*

3.90

4353

5

Cathepsin G

CTSG

0.0001*

3.83

42

3

Neutrophil defensin 1

DEFA1 and DEFA1B

0.0002*

3.59

40

2

Actin, cytoplasmic 1

ACTB

0.0079*

3.36

17

5

Trypsin-3

PRSS3

0.0002*

2.87

23

1

Immunoglobulin lambda variable 2–14

IGLV2-14

0.0073*

2.41

24

1

Complement C1q subcomponent subunit A

C1QA

< 0.0001*

2.37

30

2

Uncharacterized protein ZSWIM9

ZSWIM9

0.0001*

2.00

121

1

Properdin

CFP

0.0146

1.94

203

7

Complement C1q subcomponent subunit C

C1QC

0.0004*

1.84

217

3

Haptoglobin

HP

0.0050*

1.76

2155

13

Keratin-associated protein 13 − 2

KRTAP13-2

0.0039*

1.61

8

2

Complement C1q subcomponent subunit B

C1QB

0.0012*

1.58

217

6

alpha-1-microglobulin/bikunin precursor

AMBP

0.0016*

1.52

7786

29

  1. PSMs, peptide-spectrum matches.
  2. *Meeting the criteria of FDR < 0.05 and s0 = 0.1.
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