Fig. 4
From: A novel method of quantifying retinal vascular tortuosity in retinopathy of prematurity

Receiver operating characteristic curves for diagnostic performance of the software on vessel tortuosity at each region of interest. Curves closer to the top-left corner indicate better diagnostic performance (sensitivity 100%, specificity 100%). Diagnostic accuracy was lower at multiplier 2 (AUC = 0.56), but substantially improved from multiplier 8 (AUC = 0.90) onwards, reaching ideal performance (AUC = 1.00) at multipliers of 14 and above. Data at multiplier 20 were insufficient for analysis due to insufficient peripheral vessel image resolution.