Table 1 Annual percentage change for peripheral artery disease-related deaths among U.S. adults aged ≥ 25 years with hyperlipidemia, 1999 to 2024.

From: Trends and disparities in mortality associated with peripheral artery disease and hyperlipidemia, 1999–2024

Demographics

Trend 1

Trend 2

Trend 3

Trend 4

Trend 5

Trend 6

 

Year

AAPC

Year

APC

Year

APC

Year

APC

Year

AAPC

Year

APC

Overall

1999–2024

6.32* (5.65 to 7.00)

1999–2001

35.40* (20.27 to 47.96)

2001–2006

6.95* (3.18 to 10.80)

2006–2018

1.73* (0.02 to 2.20)

2018–2021

12.92* (8.80 to 15.30)

2021–2024

0.68 (−4.03 to 3.18)

Sex

Female

1999–2024

4.89* (4.39 to 5.69)

1999–2005

10.42* (6.59 to 16.82)

2005–2018

1.34 (− 0.39 to 2.23)

2018–2021

13.69* (7.66 to 17.03)

2021–2024

1.38 (−4.27 to 5.06)

  

Male

1999–2024

6.40* (5.72 to 7.29)

1999–2001

35.37* (19.77 to 51.91)

2001–2005

8.84* (3.05 to 12.76)

2005–2018

2.15 (− 0.53 to 2.67)

2018–2021

11.92* (7.73 to 14.31)

2021–2024

−0.23 (−4.16 to 2.13)

Race

Non-Hispanic Asian or Pacific Islander

1999–2024

3.93* (3.38 to 4.77)

          

Non-Hispanic Black

1999–2024

6.34* (5.68 to 6.90)

1999–2004

19.16* (13.77 to 28.43)

2004–2018

2.50* (1.54 to 3.18)

2018–2021

15.66* (10.41 to 18.50)

2021–2024

−0.33 (−5.32 to 2.70)

  

Non-Hispanic White

1999–2024

6.82* (6.20 to 7.67)

1999–2001

35.45* (21.43 to 45.79)

2001–2006

7.15* (3.49 to 11.03)

2006–2018

1.53 (− 0.43 to 2.07)

2018–2021

12.79* (8.69 to 15.19)

2021–2024

1.42 (−2.93 to 3.73)

Hispanic

1999–2024

7.12* (5.92 to 8.52)

1999–2001

40.45* (11.88 to 65.82)

2001–2017

3.95* (2.41 to 4.72)

2017–2021

12.74* (9.08 to 17.39)

2021–2024

−1.96 (−6.82 to 1.65)

  

Census Region

Northeast

1999–2024

6.50* (5.78 to 7.62)

1999–2001

27.36* (11.24 to 46.14)

2001–2012

5.43* (4.06 to 6.91)

2012–2017

 − 0.22 (− 6.41 to 2.28)

2018–2020

15.80* (9.81 to 20.27)

2020–2024

2.06 (−2.48 to 4.32)

Midwest

1999–2024

5.45* (4.61 to 6.45)

1999–2001

39.15* (20.33 to 58.65)

2001–2006

8.05* (1.89 to 12.54)

2006–2018

 − 0.07 (− 4.25 to 0.75)

2018–2021

11.62 (5.03 to 15.28)

2021–2024

−1.39 (−8.32 to 2.93)

South

1999–2024

5.67* (5.23 to 6.32)

1999–2005

12.10 * (8.95 to 16.75)

2005–2017

0.60 (− 0.49 to 1.40)

2017–2021

14.72* (11.53 to 19.86)

2021–2024

2.42 (−1.74 to 5.58)

  

West

1999–2024

6.62* (5.35 to 8.65)

1999–2001

45.05* (12.13 to 83.35)

2001–2024

3.81* (3.25 to 4.32)

      

Urbanization

Rural

1999–2024

7.07* (6.34 to 8.11)

1999–2002

25.90* (17.36 to 43.94)

2002–2008

5.73* (2.91 to 9.38)

2008–2018

0.73 (− 2.67 to 1.52)

2018–2020

18.35* (9.93 to 23.80)

  

Urban

1999–2024

6.90* (6.06 to 7.64)

1999–2001

3.04* (19.45 to 45.61)

2001–2006

6.68* (2.94 to 10.81)

2006–2018

1.90 (− 1.26 to 2.46)

2018–2020

14.27* (8.35 to 19.63)

  
  1. * indicate statistically significant trend.