Table 3 Pairwise comparisons of the association between change in proteinuria status and occurrence of venous thromboembolism including deep vein thrombosis, pulmonary thromboembolism, and other venous thromboses.

From: Improvement in proteinuria attenuates the occurrence of venous thromboembolism: A population-based cohort study

 

Multivariable adjusted

HR (95% CI)

p value

Venous thromboembolism

Improved vs. Normal (reference)

1.18 (1.10, 1.27)

< 0.001

Progressed vs. Normal (reference)

1.31 (1.23, 1.40)

< 0.001

Persistent vs. Normal (reference)

1.88 (1.61, 2.19)

< 0.001

Improved vs. Persistent (reference)

0.69 (0.58, 0.82)

< 0.001

Progressed vs. Persistent (reference)

0.76 (0.64, 0.90)

0.001

Improved vs. Progressed (reference)

0.91 (0.82, 1.00)

0.043

Deep vein thrombosis

Improved vs. Normal (reference)

1.10 (0.97, 1.24)

0.135

Progressed vs. Normal (reference)

1.27 (1.14, 1.41)

< 0.001

Persistent vs. Normal (reference)

2.02 (1.57, 2.59)

< 0.001

Improved vs. Persistent (reference)

0.61 (0.46, 0.80)

< 0.001

Progressed vs. Persistent (reference)

0.70 (0.53, 0.92)

0.011

Improved vs. Progressed (reference)

0.87 (0.77, 0.07)

0.024

Pulmonary thromboembolism

Improved vs. Normal (reference)

1.04 (0.88, 1.23)

0.623

Progressed vs. Normal (reference)

1.24 (1.07, 1.44)

0.005

Persistent vs. Normal (reference)

1.65 (1.14, 2.37)

0.007

Improved vs. Persistent (reference)

0.67 (0.48, 0.89)

0.047

Progressed vs. Persistent (reference)

0.81 (0.75, 0.89)

0.030

Improved vs. Progressed (reference)

0.85 (0.78, 0.93)

0.044

Other venous thromboses

Improved vs. Normal (reference)

1.28 (1.17, 1.42)

< 0.001

Progressed vs. Normal (reference)

1.44 (1.31, 1.57)

< 0.001

Persistent vs. Normal (reference)

1.88 (1.52, 2.33)

< 0.001

Improved vs. Persistent (reference)

0.75 (0.59, 0.95)

0.016

Progressed vs. Persistent (reference)

0.81 (0.69, 0.93)

0.024

Improved vs. Progressed (reference)

0.90 (0.84, 0.97)

0.011

  1. Multivariable model was adjusted for age, sex, body mass index, household income, smoking status, alcohol consumption, regular exercise, comorbidities, and the Charlson Comorbidity Index.
  2. HR, hazard ratio, CI, confidence interval.