Table 5 Total antioxidant capacity and enzymatic activity.

From: Intratesticular copper oxide nanoparticles induce dose-dependent chemical castration in male mice

Analysis

C

Sham

CuO NPs-5

CuO NPs-10

CuO NPs-20

CuO NPs-40

TAC (mmol/g protein)

0.95 ± 0.02a

0.93 ± 0.01 ab

0.90 ± 0.03b

0.85 ± 0.02c

0.72 ± 0.05d

0.53 ± 0.005e

GPx (U/mg protein)

0.32 ± 0.007a

0.30 ± 0.006 ab

0.28 ± 0.003b

0.24 ± 0.004c

0.19 ± 0.003d

0.12 ± 0.002e

SOD (U/mg protein)

7.61 ± 0.13a

7.54 ± 0.24a

6.81 ± 0.27b

5.59 ± 0.38c

4.13 ± 0.23d

2.24 ± 0.03e

CAT (U/mg protein)

22.47 ± 0.49a

21.32 ± 0.54a

18.60 ± 0.43b

15.95 ± 0.75c

10.85 ± 0.84d

5.08 ± 0.56e

MDA (nmol/g protein)

3.53 ± 0.07e

3.69 ± 0.04e

5.89 ± 0.36d

7.54 ± 0.55c

10.69 ± 0.73b

14.39 ± 1.24a

  1. C: control; CuO NPs-5: 5 mg/mL Copper oxide nanoparticles; CuO NPs-10: 10 mg/mL Copper oxide nanoparticles; CuO NPs-20: 20 mg/mL Copper oxide nanoparticles; CuO NPs-40: 40 mg/mL Copper oxide nanoparticles; TAC: Total antioxidant capacity; GPx: glutathione peroxidase; SOD: superoxide dismutase; CAT: catalase; MDA: malondialdehyde; NO: nitric oxide. a-eDifferent superscripts within the same row demonstrate significant differences (p ≤ 0.05; mean ± SD).