Fig. 10 | Scientific Reports

Fig. 10

From: Transcriptomic analysis reveals the potential role of TOE1 in hepatocellular carcinoma

Fig. 10

TOE1 knockdown widely affects the gene expression profile in HepG2 cells. (A) Distribution of gene expression in NC and TOE1 knockdown samples. (B) The Pearson correlation analysis results revealed high transcriptional concordance between NC and siTOE1-treated samples. (C) TOE1 expression quantified by RNA sequencing data. (D) Volcano plot of TOE1-Knockdown Transcriptome. Differentially expressed genes (DEGs) were identified in TOE1-depleted cells compared to scramble controls (|log2FC|>0.26, adjusted P < 0.01). (E) A heatmap was created to display the expression levels of each DEG. **P < 0.01; NC, non-specific control; siTOE1, TOE1 knockdown.

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