Fig. 9 | Scientific Reports

Fig. 9

From: KAL suppresses cholangiocarcinoma growth via downregulating miR-21 and modulating the PTEN/AKT signaling pathway

Fig. 9

miR-21 reverses the effects of KAL on the AKT pathway and apoptosis-related protein expression in CCA cells. (A) Western blot analysis of Cleaved-Caspase3, PTEN, AKT, P-AKT, MTOR, P-MTOR, and BCL-2 protein expression levels in HUCCT1 cells. (B) Western blot analysis of Cleaved-Caspase3, PTEN, AKT, P-AKT, MTOR, P-MTOR, and BCL-2 protein expression levels in RBE cells (n ≥ 3; *P < 0.05 vs. OE-KAL; #P < 0.05 vs. OE-KAL + mimic NC).

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