Table 2 Identification of the ten most responsive differentially expressed proteins upon 7-OCT treatment.
Uniprot ID | Gene | Description | Log2 fold change | − Log10 p-value |
|---|---|---|---|---|
Top-10 upregulated proteins | ||||
Q0VDF9 | HSPA14 | Heat shock 70 kDa protein 14 | 4.03 | 3.98 |
P20674 | COX5A | Cytochrome c oxidase subunit 5 A | 2.80 | 2.35 |
Q9BXP5 | SRRT | Serrate RNA effector molecule homolog | 2.68 | 2.01 |
Q9NRY5 | FAM114A2 | Protein FAM114A2 | 2.43 | 2.06 |
Q8WX92 | NELFB | Negative elongation factor B | 2.40 | 1.40 |
O15355 | PPM1G | Protein phosphatase, Mg2+/Mn2 + dependent 1G | 2.39 | 2.43 |
O95817 | BAG3 | BAG family molecular chaperone regulator 3 | 2.37 | 2.67 |
Q09161 | NCBP1 | Nuclear cap-binding protein subunit 1 | 2.23 | 1.49 |
Q16881 | TXNRD1 | Thioredoxin reductase 1, cytoplasmic | 2.12 | 2.48 |
Q07352 | ZFP36L1 | mRNA decay activator protein ZFP36L1 | 2.12 | 4.00 |
Top-10 downregulated proteins | ||||
O43665 | RGS10 | Regulator of G-protein signaling 10 | -4.78 | 2.55 |
P29590 | PML | Protein PML | -4.48 | 4.95 |
Q14232 | EIF2B1 | Translation initiation factor eIF-2B subunit alpha | -3.92 | 1.54 |
Q7KZ85 | SUPT6H | Transcription elongation factor SPT6 | -3.69 | 2.93 |
Q15582 | TGFBI | Transforming growth factor-beta-induced protein ig-h3 | -3.65 | 4.47 |
P62308 | SNRPG | Small nuclear ribonucleoprotein G | -3.41 | 2.67 |
Q14166 | TTLL12 | Tubulin–tyrosine ligase-like protein 12 | -3.27 | 4.71 |
Q9UIG0 | BAZ1B | Interleukin enhancer-binding factor 3 | -3.20 | 2.00 |
Q00535 | CDK5 | Cyclin-dependent kinase 5 | -3.15 | 3.21 |
