Table 1 Comparison of outcomes after propensity score matching.
Outcomes | Total (n = 2103) | Fentanyl (n = 701) | Morphine (n = 701) | Hydromorphone (n = 701) | p value |
|---|---|---|---|---|---|
Primary outcome | |||||
POD, n (%) | 297 (14.1) | 155 (22.1) | 74 (10.6) | 68 (9.7) | < 0.001 |
Secondary outcomes | |||||
ICU mortality, n (%) | 24 (1.1) | 14 (2.0) | 9 (1.3) | 1 (0.1) | 0.004 |
Hospital mortality, n (%) | 28 (1.3) | 16 (2.3) | 8 (1.1) | 4 (0.6) | 0.017 |
ICU length of stay, days, Median (IQR) | 1.5 (1.2–3.2) | 2.0 (1.3–3.5) | 1.5 (1.2–3.2) | 1.4 (1.2–2.4) | < 0.001 |
hospital length of stay, days, Median (IQR) | 7.0 (5.3–9.9) | 7.8 (5.7–11.3) | 6.7 (5.1-9.0) | 6.9 (5.3–9.7) | < 0.001 |
Vasopressor-free days within 28 days, Mean ± SD | 26.7 ± 4.1 | 26.1 ± 5.5 | 26.8 ± 3.7 | 27.3 ± 2.1 | < 0.001 |
Ventilator-free days within 28 days, Mean ± SD | 26.9 ± 4.0 | 26.3 ± 5.3 | 26.9 ± 3.8 | 27.5 ± 2.0 | < 0.001 |