Table 3 Threshold effect analysis of relationship of fibrinogen with one year mortality rate.

From: U shaped association between fibrinogen and one year mortality in women undergoing coronary artery bypass grafting

 

Mortality rate

Adjusted HR (95% CI)

P value

Two model

 

Fibrinogen ≤ 174

0.969 (0.947, 0.991)

0.0068

Fibrinogen ≥ 174

1.0057 (1.0001, 1.0114)

0.0471

Likelihood Ratio test

–

0.002

Non-linear Test*1

–

0.005

Non-linear Test*2

–

0.004

  1. Solid and dashed lines represent the predicted value and 95% confidence intervals.
  2. Adjusted for demographic variables (age, BMI), Basic vital signs (heart rate, ABPS, ABPD, Temperature), Blood biochemical indicators (WBC, RBC, platelet count, sodium, potassium, calcium total, chloride, glucose, anion gap, lactate, urea nitrogen, creatinine) SOFA, APS Ⅲ, SAPSⅡ, GCS, CHARLSON.
  3. Abbreviations: the unit of fibrinogen is mmol/L, BMI: body mass index; ABPS: Arterial systolic pressure; ABPD: Arterial diastolic pressure; WBC: white blood cell count; RBC: red blood cell count; sofa: Sequential Organ Failure Assessment; APS Ⅲ: Acute Physiology and Chronic Health Evaluation Ⅲ; SAPSⅡ: simplified acute physiology score ii; GCS: Glasgow Coma Scale; CHARLSON: Charlson comorbidity index; AKI: acute kidney injury; CRRT: Continuous Renal Replacement Therapy.
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