Table 1 Subgroup analysis.
Characteristics | OS | DSS | DFS | |||
|---|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
Patient age, years | ||||||
≤ 60 | 0.714 (0.592–0.861) | < 0.001 | 0.567 (0.391–0.823) | = 0.003 | 0.585 (0.507–0.675) | < 0.001 |
61–70 | 0.790 (0.670–0.932) | = 0.005 | 0.496 (0.303–0.811) | = 0.005 | 0.371 (0.293–0.468) | < 0.001 |
71–80 | 0.683 (0.602–0.773) | < 0.001 | 0.540 (0.365–0.799) | = 0.002 | 0.517 (0.373–0.717) | < 0.001 |
> 80 | 0.569 (0.484–0.669) | < 0.001 | 0.850 (0.503–1.435) | = 0.543 | 0.331 (0.167–0.656) | = 0.002 |
Tumor size (mm) | ||||||
≤ 2 | 0.658 (0.496–0.872) | = 0.004 | 1.088 (0.521–2.272) | = 0.822 | 0.497 (0.325–0.760) | = 0.001 |
2–10 | 0.477 (0.429–0.532) | < 0.001 | 0.466 (0.355–0.648) | < 0.001 | 0.495 (0.420–0.584) | < 0.001 |
> 10 | 0.380 (0.341–0.423) | < 0.001 | 0.348 (0.258–0.470) | < 0.001 | 0.531 (0.453–0.622) | < 0.001 |
ER status | ||||||
Negative | 0.416 (0.349–0.495) | < 0.001 | 0.334 (0.209–0.535) | < 0.001 | 0.575 (0.446–0.740) | < 0.001 |
Positive | 0.447 (0.412–0.485) | < 0.001 | 0.463 (0.365–0.586) | < 0.001 | 0.498 (0.441–0.563) | < 0.001 |
Nuclear grade | ||||||
1 | 0.456 (0.381–0.546) | < 0.001 | 0.501 (0.280–0.898) | = 0.020 | 0.519 (0.383–0.705) | < 0.001 |
2 | 0.467 (0.417–0.522) | < 0.001 | 0.476 (0.343–0.659) | < 0.001 | 0.442 (0.370–0.528) | < 0.001 |
3 | 0.425 (0.377–0.479) | < 0.001 | 0.368 (0.267–0.506) | < 0.001 | 0.540 (0.458–0.637) | < 0.001 |
