Fig. 10

A The Cnet map depicts the relationship of the top ten hub genes with the tertiary granule lumen, indicating their involvement in cellular components. The corresponding dot plot depicts important cellular components as large red dots (indicating low p-values), while non-significant terms are represented by blue or purple dots. B The Cnet figure shows the N-acyltransferase activity associated with the top ten hub genes, illustrating their functional linkage to molecular processes. Large red dots on the dot plot represent statistically significant molecular functions, while blue or purple dots signal less significant results. C The Cnet map depicts the participation of the top 10 hub genes in sphingolipid metabolism pathways, with large red dots representing major routes and blue/purple dots representing non-significant keywords. D Finally, the Cnet plot further emphasizes the importance of the top hub genes in the ceramide metabolism pathway. The dot plot depicts importance, with red dots indicating important routes based on p-values and blue/purple dots corresponding to pathways with lower statistical relevance.