Table 2 Experimental results of response surface.

From: Extraction process and antioxidant and antimicrobial activities of total flavonoids from Broussonetia papyrifera leaves

Runs

A

B

C

D

Y

Solid-to-liquid ratio/g/mL

Extraction time/min

Extraction temperature/℃

Ethanol volume fraction/%

Total flavonoid yield/%

1

1

-1

0

0

5.64

2

0

0

− 1

1

4.58

3

1

1

0

0

4.81

4

0

0

0

0

5.56

5

0

0

1

− 1

4.67

6

− 1

0

1

0

4.81

7

1

0

− 1

0

4.45

8

0

1

0

1

4.21

9

− 1

-1

0

0

4.49

10

0

-1

0

− 1

4.39

11

− 1

1

0

0

4.35

12

0

-1

− 1

0

4.56

13

0

-1

0

1

4.91

14

0

1

-1

0

4.57

15

0

1

1

0

4.89

16

0

0

1

1

5.21

17

1

0

0

1

5.23

18

0

-1

1

0

5.44

19

0

0

0

0

5.78

20

0

0

-1

− 1

3.91

21

0

1

0

− 1

4.83

22

1

0

0

− 1

4.93

23

− 1

0

-1

0

3.93

24

− 1

0

0

− 1

4.04

25

− 1

0

0

1

4.87

26

0

0

0

0

5.36

27

0

0

0

0

5.41

28

0

0

0

0

5.51

29

1

0

1

0

5.23