Fig. 2

Apoptosis measured after complement killing assay after 60 min incubation with antibodies and normal human serum (NHS). HGSOC cells were tracked from PE-Annexin V and 7-AAD positive (end stage apoptosis and death). (A) OVCAR-8 and OVCAR-3 Pt-resistant and sensitive HGSOC cells treated with S2 antibodies. (B) OVCAR-8 and OVCAR-3 Pt-resistant and sensitive HGSOC cells treated with S2+20 \({\upmu }\)g/ml Yth53.1 antibodies. (C) OVCAR-4 (262, 264, WT) cells treated with S2 alone. (D) OVCAR-4 (262, 264, WT) cells treated with S2 +20 \({\upmu }\)g/ml Yth53.1.